There are a number of big games again this weekend, as we get to crunch time in the domestic leagues around Europe. Here are the pick of the matches, starting with a cracker in Italy…..

Juventus v Inter Milan

Inter Milan seek a fourth successive Serie A win when they travel to a Juventus side still harbouring ambitions of winning the Scudetto (Inter 8/5 to beat Juve).

The defending champions are five points adrift of Milan and just two points behind second-placed Napoli with a game in hand.

Juventus, despite trailing the leaders by 11 points and sitting in eighth place, will be relishing the fixture.

“Inter versus Juve or Juve versus Inter have always been important games, always charged with tension,” said Inter president Massimo Moratti.

“The important thing is that everything goes smoothly. We know it’s an important game for us and for them.

“It’s always been the derby d’Italia and, regardless of the teams’ positions in the standings, it remains like that.”

It’s a game that is crucial to Inter’s Scudetto chances, feels their midfielder Wesley Sneijder. The Nerazzurri have two massive games on the horizon, as they go to Fiorentina on Wednesday.

“We are closing the gap with Milan,” said Sneijder. “If we win against Juventus and Fiorentina then I really think we can win the Scudetto.

“The game at Juve is crucial for us while we also cannot miss the opportunity to gain ground when we face Fiorentina.”

Juve halted a run of three games without a win by beating Cagliari 3-1 in Sardinia in the last round (Juventus 7/4 to beat Inter), but have won just one of their last three games at Turin’s Stadio Olimpico.

“We saw the real Juve against Cagliari,” said Juve defender Andrea Barzagli. “Now we are looking to find continuity in results. I expect an open game, with this game crucial for both sides.”

Inter will be without Argentina striker Diego Milito, who is sidelined for a month with a thigh injury, as well as suspended defender Cristian Chivu.

Juve have recovered midfielder Claudio Marchisio, who sustained a muscular injury against Cagliari.

Deportivo La Coruna v Villareal

Villarreal, third placed going into Sunday’s away trip, bid to bounce back from a 1-0 defeat to Levante last time out (Villareal 21/20 to beat Deportivo).

Juan Carlos Garrido’s men had looked unstoppable on their own patch prior to that defeat, and with Valencia breathing down their necks in the race for third spot, they can ill afford further slip-ups.

Giuseppe Rossi, however, is enjoying the best form of his career, topped off with an international goal for Italy in the week.

Deportivo are struggling, and Miguel Angel Lotina has been under further pressure this week after last weekend’s hammering at Getafe (Deportivo 12/5 to beat Villareal).

This game arrives a week too soon for Deportivo winger Andres Guardado, who is due back in training within the next seven days.

Villareal striker Marco Ruben is doubtful, while defender Angel is out for the entire campaign, but Nilmar returned to action last week and is likely to start.

The home team have been largely disappointing and are currently sitting in 17^th, with only a point separating them from the bottom three.

However, the Yellow Submarines’ last two visits to the Riazor ended in losses for them and of their 12 visits they have won three and drawn two – the last victory coming on the final day of the season in May 2008.

Roda JC v Ajax

Ajax coach Frank de Boer has left his side in no doubt about his feelings following last weekend’s 2-0 win against De Graafschap (Ajax 17/10 to beat Roda).

Ajax picked up the points, but de Boer was far from satisfied and wants an improvement against Roda.

“I think this match may determine our course for the remainder of this season”, de Boer said. “The away game at Roda is a traditional tough one, but I feel like we are ready. We’ll have to do better than last week against De Graafschap, because if we don’t, we’ll lose for sure.”

This fixture is statistically likely to end in a draw – the teams have finished all-square in 15 of the 37 meetings, including last season?s 2-2 draw.

Mounir El Hamdaoui scored twice when Ajax beat Roda at home earlier in the season, and is set to feature again, though de Boer is not saying whether he will use him up front or as a left winger.

Gregory van der Wiel, who played in the 3-1 win of the Netherlands against Austria on Wednesday, is suspended.

Roda JC will miss Laurent Delorge, who is still out with a back injury. The midfielder who played four Eredivisie matches for Ajax in the 2007/2008 season, has been a key figure for Roda this season (Roda 16/5 to beat Ajax).

Lille v Toulouse

Lille will still be on top of the table when they tackle Toulouse on Sunday, but could have had their advantage cut to two points if PSG win on Saturday (Lille 4/9 to beat Toulouse).

Lille have only lost twice this season, and are five points ahead of PSG with a goal difference that is eight better. Toulouse are seventh in the table but on a reasonable run, having won four of their last eight games.

Goalkeeper Mickael Landreau, who signed a contract extension this week to keep him with the club until summer 2014, will make his 500th Ligue 1 appearance.

However, rather than focusing on his own achievement, Landreau, who signed from Paris St Germain in summer 2009, is concentrating on helping Lille to victory as they look to maintain a healthy lead.

Landreau said: “The most important thing is to get the win. To be on top of the table, after all these years, is something fantastic.

“My approach remains the same: I’ve always been meticulous in my preparation. I must say that, for my 500th, I’m very happy to play it at home rather than on the road.

“I’ve always had a good relationship with the LOSC fans and it has been at this club that I’ve found everything I was looking for: ambition, serenity and enjoyment.”

Toulouse manager Alain Casanova believes Lille have all the necessary qualities to become champions (Toulouse 11/2 to beat Lille).

He told www.tfc.info: “They produce a quality game and have great spirit, especially attacking-wise. They have principles that have been the same for quite some time.

“This is a team capable of being very aggressive and very reactive as soon as they have lost the ball.

“This team has everything to challenge for the title and advance with it today.”

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