Tottenham Hotspur could have a thankless night ahead of them when travel across the Irish Sea to take on Shamrock Rovers in the Europa League on Thursday (Shamrock 6/1, draw 7/2, Spurs 4/9 in the match betting).
Spurs could pick up all three points at the Tallaght Stadium and still find themselves out of the second tier competition as they currently sit in third place in Group A.
The north London outfit will require all three points, PAOK to beat Rubin Kazan and a five-goal swing, if they want to reach the knockout stages of the tournament.
It looks like a tall order for Spurs, who are challenging near the top of the Premier League table and will have a return to the Champions League on their minds this season.
Spurs boss Harry Redknapp is likely to play a weakened side for the trip to Ireland but with the strength in depth at White Hart Lane, the likes of Jermain Defoe (4/1 first goalscorer), Roman Pavlyuchenko and Giovanni Dos Santos set to feature against Rovers.
The Irish outfit almost caused an upset when these two sides last met in north London as they took a one goal lead before crashing to a 3-1 defeat.
Striker Gary Twigg was the dangerman for Rovers in the first leg and Spurs will have to keep an eye on the front-man.
It’s unlikely Tottenham will reach the knockout stages of the Europa League this time around but they should have enough strength in depth to win this one comfortably.
Birmingham’s European campaign also hangs in the balance as they prepare for their clash with NK Maribor (Birmingham 8/15, draw 3/1, NK Maribor 5/1 in the match betting).
The Blues can consider themselves unlucky not to have picked up any points from their last outing in the competition, after they were on the wrong end of a 1-0 scoreline against Braga in Portugal.
Only a deflected goal from Hugo Viana was the difference between the two sides, in a game which saw Nikola Zigic miss from the penalty spot.
Birmingham will be confident going into Thursday’s game as they have already beaten Maribor 2-1 in Slovenia earlier in the season.
Dalibor Volas got on the scoresheet in the last meeting between these two sides and is priced at 10/1 to get the first goal at St Andrews.
City need a win if they are to stand any chance of qualifying for the last 32 and in front of their home fans, manager Chris Hughton and his side should be celebrating three points on Thursday.
The other British interest in the Europa League will see Celtic make the tough trip to Italy to take on Udinese (Udinese 8/13, draw 11/4, Celtic 9/2 in the match betting).
This Serie A outfit could have their star striker Antonio Di Natale (7/2 first goalscorer) available for selection and he can be a thorn in any teams’ side.
Udinese have enjoyed an impressive season so far as they sit in second place in the Serie A table, level on points with leaders Juventus.
Celtic will be without the likes of Joe Ledley, Glenn Loovens, Adam Matthew and Kris Commons for the trip to the continent which makes a tough test even harder.
Udinese should win this one against the Old Firm side, who might just be out of their depth in the fiery atmosphere at the Stadio Friuli.
Want £200 Free? Click here to visit Bet365 and claim your free money.